Well, I like the stroker 400 specifically because of the smaller mains. That leaves more meat in the main webs, and therefore 400 blocks are stronger. I haven't looked recently, but there used to be 4.21" stroke cranks available in 3.00" mains. Put one of those in a +0.030 400 and you have a standard bore 455. Or, do what I did and go with a 4.25" stroke and a +0.035 overbore, and you have a 461. The other advantage of the smaller mains is they tend to oil better - the larger journals "try harder" to fling the oil out of the bearings.
To be totally honest though, if you're building a purely street cruiser that's not going to see much if any strip time, a "regular" larger journal 455 will work just fine.
On either engine, it would be worth your while to put some effort into locating a set of 6x-4 heads. Run those in either a 455 or a 461 with stock head gaskets, flat top pistons and you're at 9.2:1 if you don't zero deck the block, 9.5:1 if you do. Either engine would have good to very good quench characteristics (much better than it would with big 'ol dishes in the pistons). --and the parts should be cheaper to boot.